Anti-AIMP2抗體,AIMP2抗體產品詳細資料
產品編號 BYK-2509R
英文名稱 AIMP2
中文名稱 AIMP2抗體
別 名 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Aimp2; AA407136; AA407225; Aimp2(p38); JTV 1 protein; Jtv1; MGC30261; MGC36346; MGC36522; MGC37389; ARS interacting multi functional protein 2; Multisynthetase complex auxiliary component p38; P38; tRNA SYNTHETASE COFACTOR p38; PRO0992; Protein JTV 1; JTV-1; JTV1; P38; PRO0992; AIMP2_HUMAN.
研究領域 細胞生物 免疫學 神經生物學 信號轉導
分 子 量 36kDa
抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產品應用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產品應用不做依據，具體產品應用與實驗稀釋比請！
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
亞 型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Anti-AIMP2抗體,AIMP2抗體產品介紹
P38 is a probable core protein of the multisynthetase complex that serves as a template for the assembly of the supramolecular structure. Mediates ubiquitination of FUBP1 and its degradation by the proteasome. P38 is also a cofactor of multi-ARS complex and also a substrate of parkin in neuronal cell.
Function:
Required for assembly and stability of the minoacyl-tRNA synthase complex. Mediates ubiquitination and egradation of FUBP1, a transcriptional activator of MYC, leading o MYC down-regulation which is required for aveolar type II cell ifferentiation. Blocks MDM2-mediated ubiquitination and egradation of p53/TP53. Functions as a proapoptotic factor.
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