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LabChip^® EZ Reader uses a microfluidic chip technology based on a mobility shift principle. Assays utilizing fluorescently-labeled substrates are set up in polypropylene microplates. As the experiment is being run in the microplate, small volumes of each assay are "sipped" up into the LabChip microfluidic chip. The LabChip multi-sipper chips comprise small channels connected to upstream and downstream electrodes. As the reaction moves through these channels, the reaction components are separated into substrate and product (or starting material and end material) via differences in their mobility. These differences in mobility are related to the charge/mass ratio of each component (substrate, product, etc.). As each component reaches the detection window on the chip, a fluorescent peak is recorded.